Kumar, K. Vijay and Verma, Reena (2021) Anti-Cancer Effect of Novel Hydroxy Flavons on Human Cancer Cell In vitro and In silico. Journal of Pharmaceutical Research International, 33 (61B). pp. 193-199. ISSN 2456-9119
5393-Article Text-7523-2-10-20221006.pdf - Published Version
Download (490kB)
Abstract
Anti-cancer effect of 7 hydroxy Favone and its derivatives were tested against human cancer cell lines such MCF-7 cell line using the in vitro by MTT assay in cancer cell lines. All the favones showed significant activity against all pathogens. 7-HF showed a maximum zone of inhibition against cancer cell lines. 7-try hydroxy flavones showed the lowest anti-cancer activity. And docking results shown as 7-HF has shown maximum docking -7.9, 7,8,3’-THF has -7.5 and 7,3’,4’ has -7.7. as per the results, 7 hydroxy flavone could be a possible source to obtain new and effective compounds to treat cancer.
Item Type: | Article |
---|---|
Subjects: | Archive Digital > Medical Science |
Depositing User: | Unnamed user with email support@archivedigit.com |
Date Deposited: | 27 Feb 2023 10:25 |
Last Modified: | 19 Feb 2024 04:18 |
URI: | http://eprints.ditdo.in/id/eprint/126 |