Anti-Cancer Effect of Novel Hydroxy Flavons on Human Cancer Cell In vitro and In silico

Kumar, K. Vijay and Verma, Reena (2021) Anti-Cancer Effect of Novel Hydroxy Flavons on Human Cancer Cell In vitro and In silico. Journal of Pharmaceutical Research International, 33 (61B). pp. 193-199. ISSN 2456-9119

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Abstract

Anti-cancer effect of 7 hydroxy Favone and its derivatives were tested against human cancer cell lines such MCF-7 cell line using the in vitro by MTT assay in cancer cell lines. All the favones showed significant activity against all pathogens. 7-HF showed a maximum zone of inhibition against cancer cell lines. 7-try hydroxy flavones showed the lowest anti-cancer activity. And docking results shown as 7-HF has shown maximum docking -7.9, 7,8,3’-THF has -7.5 and 7,3’,4’ has -7.7. as per the results, 7 hydroxy flavone could be a possible source to obtain new and effective compounds to treat cancer.

Item Type: Article
Subjects: Archive Digital > Medical Science
Depositing User: Unnamed user with email support@archivedigit.com
Date Deposited: 27 Feb 2023 10:25
Last Modified: 19 Feb 2024 04:18
URI: http://eprints.ditdo.in/id/eprint/126

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