PREVENTION OF Porphyromonas gingivalis CAUSING GUM DISEASE BY Salvia rosmarinus

Porphyromonas gingivalis is known as the causal organism of gum disease. One of the key enzymes involved in its biochemical pathway is gingipain R. The Biovia Discovery Studio is used to study about the molecular docking of phytochemicals with the enzyme. The strength of the interaction was evaluated based on -CDOCKER energy and -CDOCKER interaction energy. High positive values for both the parameters indicated that out of different phytochemicals, alcohol can effectively deactivate the gingipain R enzyme thereby interrupting the life cycle of Porphyromonas gingivalis.